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Cocaine Addiction Effects of the Brain: Binge and Craving
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Cocaine afflicts many individuals and is potently addictive. Originally hailed as a wonder-drug in the late 19th century, cocaine is now considered an illegal substance. Cocaine’s addictive properties can be attributed to changes in the dopamine reward pathway of the Ventral Tegmental Area and Substantia Nigra, Prefrontal Cortex, Dorsal Striatum, Nucleus Accumbens, Amygdala, Globus Pallidus, and Hippocampus. This drug affects the brain in two processes: binge and crave. The binge process highlights cocaine’s ability to block dopamine reuptake from the synapse resulting in hyperstimulation of the postsynaptic neuron in the dopamine reward pathway. The crave process promotes drug-seeking behavior through conditional and contextual cues. Understanding the effects of cocaine in the brain may grant insight in creating future medication and therapies to treat individuals addicted to this drug.

Subject:
Arts and Humanities
Biology
Life Science
Psychology
Social Science
Visual Arts
Material Type:
Lecture
Provider:
CUNY Academic Works
Provider Set:
City College
Author:
Apte, Advait
Cahn, Anna
Chen, Ching-Jung
Cheng, Katie
Eng, Timmy
Hypolite, Lenn
Malik, Rafay
Oviedo, Hysell
Date Added:
06/28/2023
Psychology
Unrestricted Use
CC BY
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Psychology is designed to meet scope and sequence requirements for the single-semester introduction to psychology course. The book offers a comprehensive treatment of core concepts, grounded in both classic studies and current and emerging research. The text also includes coverage of the DSM-5 in examinations of psychological disorders. Psychology incorporates discussions that reflect the diversity within the discipline, as well as the diversity of cultures and communities across the globe.Senior Contributing AuthorsRose M. Spielman, Formerly of Quinnipiac UniversityContributing AuthorsKathryn Dumper, Bainbridge State CollegeWilliam Jenkins, Mercer UniversityArlene Lacombe, Saint Joseph's UniversityMarilyn Lovett, Livingstone CollegeMarion Perlmutter, University of Michigan

Subject:
Psychology
Social Science
Material Type:
Full Course
Provider:
Rice University
Provider Set:
OpenStax College
Date Added:
10/19/2022
Psychology, States of Consciousness, Substance Use and Abuse
Conditional Remix & Share Permitted
CC BY-NC
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By the end of this section, you will be able to:Describe the diagnostic criteria for substance use disordersIdentify the neurotransmitter systems affected by various categories of drugsDescribe how different categories of drugs effect behavior and experience

Subject:
Psychology
Social Science
Material Type:
Module
Date Added:
10/19/2022